• Question: How successful are your studies about saving cells of heart muscle?

    Asked by Ilya Schneider to Michael on 13 Nov 2015.
    • Photo: Michael Schneider

      Michael Schneider answered on 13 Nov 2015:


      If you were a mouse with a heart attack, scientists know many ways to shrink the damage by 75%. Finding out which approaches work best in patients is very hard! Many highly promising ideas do not succeed. But, in our experiments we believe it’s important to test human heart muscle cells as possibly a better predictor of what will work in the clinic. We can reduce the death of human heart muscle cells in a dish by 50% or more! Now, we have to do further work, to turn what we’ve made into a safe and effective drug.

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